National gateways and data access services · Health record databases
NHS England Secure Data Environment (SDE)
Also known as: NHS SDE, SDE Formerly: NHS Digital Trusted Research Environment
Not yet verified by a curator
National NHS data for England — Hospital Episode Statistics (HES), mortality, prescribing, mental health, maternity and more — analysed inside a secure environment.
Application required Fee applies TREHow it can replace animal studies
Whole-population NHS records can show how diseases develop and how treatments work in real patients.
How to get access
Application to NHS England; data stays in the SDE.
- Access level
- Application required
- Who can use it
- Approved researchers from eligible organisations.
- Cost
- Fee applies
- Secure research environment
- NHS England Secure Data Environment
Data held
Population
From Science Without Animals (https://sciencewithoutanimals.org/resource/nhs-england-secure-data-environment), release data under CC BY 4.0. Printed 13/11/2026.